About Us
Research in the Howell group encompasses projects involving method development, total synthesis and the interface of chemistry and biology. The two main foci are the synthesis and exploitation of unusual strained heterocycles and the preparation of glycosphingolipids that activate natural killer T (NKT) cells. (more...)
Research
The Group
News
- Check out our latest publicationsExciting news: our current lab members, Jason, JJ, and Tae, published their work on the synthesis of 4-bromo-2,3-dihydrofurans in Chemical Science. Additionally, a collaborative work between the Howell and the Cravatt groups on ABHD17 inhibition studies in Nature Chemical Biology has been published. Congratulations!Posted on July 21, 2021
- Congratulations Bobby for winning a summer fellowshipCongratulations to Robert “Bobby” Gilbert for winning a Dr. Charles Waring Chemistry Scholarship. He is working this summer on the synthesis of glycopshingolipids that activate iNKT cells.Posted on May 26, 2021
- Check out our latest publicationsExciting news: our current group member, Pascal, published his work on chemical probe development in ChemBioChem. Additionally, our former group member, Santosh, published an article in ACS Chemical Biology about his study on the potent stimulation of iNKT cells and anti-tumor immunity in humanized mouse model by modified KRN7000. Congratulations, guys!Posted on December 22, 2020
- ACS-CVS C-H Activation SymposiumPast and current members of the Howell group had a great time at the ACS-CVS symposium on Solutions to Challenging C-C Bond formation. The first talk was given by former member Christian Malapit, who is currently undergoing a postdoc in Melanie Sanford’s lab at the University of Michigan. He did a great job, Congrats Christian! […]Posted on September 25, 2018
- Check out our newest article in Scientific ReportsDon and Katie (Katherine) helped our collaborators in the Suib group with work detailing the oxidation of amides to imides by MnO catalysts. Congrats guys!Posted on September 14, 2018
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